/* ============================================
   PHARMASSIST - PROFESSIONAL MEDICAL PLATFORM
   ============================================ */

/* CSS Variables */
:root {
    /* Colors */
    --primary: #3498db;
    --primary-dark: #2980b9;
    --secondary: #2ecc71;
    --danger: #e74c3c;
    --warning: #f39c12;
    --info: #3498db;
    
    /* Neutrals */
    --bg-primary: #1a1a1a;
    --bg-secondary: #2d2d2d;
    --bg-tertiary: #3a3a3a;
    --bg-card: #252525;
    
    --text-primary: #ffffff;
    --text-secondary: #b0b0b0;
    --text-muted: #808080;
    
    --border: #404040;
    --border-light: #505050;
    
    /* Spacing */
    --spacing-xs: 4px;
    --spacing-sm: 8px;
    --spacing-md: 16px;
    --spacing-lg: 24px;
    --spacing-xl: 32px;
    
    /* Border Radius */
    --radius-sm: 4px;
    --radius-md: 8px;
    --radius-lg: 12px;
    
    /* Shadows */
    --shadow-sm: 0 2px 4px rgba(0, 0, 0, 0.3);
    --shadow-md: 0 4px 8px rgba(0, 0, 0, 0.4);
    --shadow-lg: 0 8px 16px rgba(0, 0, 0, 0.5);
    
    /* Transitions */
    --transition: 0.2s ease;
}

/* Reset & Base Styles */
* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
}

html {
    font-size: 16px;
    -webkit-font-smoothing: antialiased;
    -moz-osx-font-smoothing: grayscale;
}

body {
    font-family: 'Inter', -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;
    background: var(--bg-primary);
    color: var(--text-primary);
    line-height: 1.6;
    min-height: 100vh;
    display: flex;
    flex-direction: column;
}

/* Typography */
h1, h2, h3, h4, h5, h6 {
    font-weight: 600;
    line-height: 1.3;
    margin-bottom: var(--spacing-md);
}

h1 { font-size: 1.75rem; }
h2 { font-size: 1.5rem; }
h3 { font-size: 1.25rem; }
h4 { font-size: 1.1rem; }

p {
    margin-bottom: var(--spacing-md);
}

/* Container */
.container {
    width: 100%;
    max-width: 1200px;
    margin: 0 auto;
    padding: 0 var(--spacing-md);
}

/* Loading Overlay */
.loading-overlay {
    position: fixed;
    top: 0;
    left: 0;
    right: 0;
    bottom: 0;
    background: rgba(0, 0, 0, 0.8);
    display: flex;
    flex-direction: column;
    align-items: center;
    justify-content: center;
    z-index: 9999;
    backdrop-filter: blur(4px);
}

.loading-overlay.hidden {
    display: none;
}

.spinner {
    width: 48px;
    height: 48px;
    border: 4px solid var(--border);
    border-top-color: var(--primary);
    border-radius: 50%;
    animation: spin 0.8s linear infinite;
}

@keyframes spin {
    to { transform: rotate(360deg); }
}

.loading-overlay p {
    margin-top: var(--spacing-md);
    color: var(--text-secondary);
}

/* Header */
.header {
    background: var(--bg-secondary);
    border-bottom: 1px solid var(--border);
    padding: var(--spacing-md) 0;
    position: sticky;
    top: 0;
    z-index: 100;
    box-shadow: var(--shadow-sm);
}

.header-content {
    display: flex;
    align-items: center;
    justify-content: space-between;
}

.logo {
    display: flex;
    align-items: center;
    gap: var(--spacing-sm);
}

.logo h1 {
    font-size: 1.5rem;
    margin: 0;
    font-weight: 700;
    background: linear-gradient(135deg, var(--primary), var(--secondary));
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent;
    background-clip: text;
}

.btn-icon {
    background: transparent;
    border: none;
    color: var(--text-secondary);
    cursor: pointer;
    padding: var(--spacing-sm);
    border-radius: var(--radius-md);
    transition: var(--transition);
}

.btn-icon:hover {
    background: var(--bg-tertiary);
    color: var(--text-primary);
}

/* Main Content */
.main-content {
    flex: 1;
    padding: var(--spacing-xl) 0;
}

/* Section Title */
.section-title {
    font-size: 1.25rem;
    margin-bottom: var(--spacing-lg);
    color: var(--text-primary);
}

/* Quick Access Cards */
.quick-access {
    margin-bottom: var(--spacing-xl);
}

.card-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(140px, 1fr));
    gap: var(--spacing-md);
}

.quick-card {
    background: var(--bg-card);
    border: 1px solid var(--border);
    border-radius: var(--radius-lg);
    padding: var(--spacing-lg);
    text-align: center;
    cursor: pointer;
    transition: var(--transition);
    display: flex;
    flex-direction: column;
    align-items: center;
    gap: var(--spacing-sm);
}

.quick-card:hover {
    background: var(--bg-tertiary);
    border-color: var(--primary);
    transform: translateY(-2px);
    box-shadow: var(--shadow-md);
}

.quick-card-icon {
    font-size: 2rem;
    margin-bottom: var(--spacing-xs);
}

.quick-card h3 {
    font-size: 1rem;
    margin: 0;
    color: var(--text-primary);
}

.quick-card p {
    font-size: 0.875rem;
    color: var(--text-secondary);
    margin: 0;
}

/* Calculator Section */
.calculator-section {
    background: var(--bg-card);
    border-radius: var(--radius-lg);
    padding: var(--spacing-lg);
    box-shadow: var(--shadow-md);
}

/* Module Navigation */
.module-nav {
    display: flex;
    gap: var(--spacing-xs);
    margin-bottom: var(--spacing-lg);
    overflow-x: auto;
    padding-bottom: var(--spacing-sm);
    scrollbar-width: thin;
    scrollbar-color: var(--border) transparent;
}

.module-nav::-webkit-scrollbar {
    height: 6px;
}

.module-nav::-webkit-scrollbar-track {
    background: transparent;
}

.module-nav::-webkit-scrollbar-thumb {
    background: var(--border);
    border-radius: 3px;
}

.module-tab {
    background: var(--bg-tertiary);
    border: 1px solid var(--border);
    color: var(--text-secondary);
    padding: var(--spacing-sm) var(--spacing-md);
    border-radius: var(--radius-md);
    cursor: pointer;
    transition: var(--transition);
    white-space: nowrap;
    font-size: 0.875rem;
    font-weight: 500;
}

.module-tab:hover {
    background: var(--bg-secondary);
    color: var(--text-primary);
}

.module-tab.active {
    background: var(--primary);
    border-color: var(--primary);
    color: white;
}

/* Module Content */
.module-content {
    display: none;
}

.module-content.active {
    display: block;
    animation: fadeIn 0.3s ease;
}

@keyframes fadeIn {
    from { opacity: 0; transform: translateY(10px); }
    to { opacity: 1; transform: translateY(0); }
}

.module-header {
    margin-bottom: var(--spacing-lg);
}

.module-header h2 {
    margin-bottom: var(--spacing-sm);
}

.module-description {
    color: var(--text-secondary);
    font-size: 0.9375rem;
    margin: 0;
}

/* Sub-Module Navigation */
.sub-module-nav {
    display: flex;
    gap: var(--spacing-sm);
    margin-bottom: var(--spacing-lg);
    flex-wrap: wrap;
}

.sub-tab {
    background: var(--bg-secondary);
    border: 1px solid var(--border);
    color: var(--text-secondary);
    padding: var(--spacing-sm) var(--spacing-md);
    border-radius: var(--radius-md);
    cursor: pointer;
    transition: var(--transition);
    font-size: 0.875rem;
}

.sub-tab:hover {
    background: var(--bg-tertiary);
    color: var(--text-primary);
}

.sub-tab.active {
    background: var(--primary);
    border-color: var(--primary);
    color: white;
}

/* Sub-Module Content */
.sub-module {
    display: none;
}

.sub-module.active {
    display: block;
    animation: fadeIn 0.3s ease;
}

/* Forms */
.calc-form {
    margin-bottom: var(--spacing-lg);
}

.form-group {
    margin-bottom: var(--spacing-md);
}

.form-group label {
    display: block;
    margin-bottom: var(--spacing-xs);
    color: var(--text-secondary);
    font-size: 0.875rem;
    font-weight: 500;
}

.form-group input,
.form-group select {
    width: 100%;
    padding: 12px;
    background: var(--bg-secondary);
    border: 1px solid var(--border);
    border-radius: var(--radius-md);
    color: var(--text-primary);
    font-size: 1rem;
    transition: var(--transition);
}

.form-group input:focus,
.form-group select:focus {
    outline: none;
    border-color: var(--primary);
    box-shadow: 0 0 0 3px rgba(52, 152, 219, 0.1);
}

.form-group input::placeholder {
    color: var(--text-muted);
}

.form-row {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: var(--spacing-md);
}

.optional {
    color: var(--text-muted);
    font-weight: 400;
    font-size: 0.8125rem;
}

/* Conversion Inputs */
.conversion-inputs {
    display: grid;
    grid-template-columns: 1fr auto 1fr;
    gap: var(--spacing-md);
    align-items: end;
}

.input-with-unit {
    display: grid;
    grid-template-columns: 1fr 120px;
    gap: var(--spacing-sm);
}

.btn-swap {
    background: var(--bg-tertiary);
    border: 1px solid var(--border);
    color: var(--text-secondary);
    padding: 12px;
    border-radius: var(--radius-md);
    cursor: pointer;
    transition: var(--transition);
    font-size: 1.25rem;
    margin-bottom: var(--spacing-md);
}

.btn-swap:hover {
    background: var(--bg-secondary);
    color: var(--primary);
    border-color: var(--primary);
}

/* Buttons */
.btn {
    padding: 12px 24px;
    border: none;
    border-radius: var(--radius-md);
    font-size: 1rem;
    font-weight: 500;
    cursor: pointer;
    transition: var(--transition);
    display: inline-flex;
    align-items: center;
    justify-content: center;
    gap: var(--spacing-sm);
}

.btn-primary {
    background: var(--primary);
    color: white;
}

.btn-primary:hover {
    background: var(--primary-dark);
    box-shadow: var(--shadow-md);
}

.btn-primary:active {
    transform: translateY(1px);
}

/* Info Banner */
.info-banner {
    background: rgba(52, 152, 219, 0.1);
    border-left: 4px solid var(--primary);
    padding: var(--spacing-md);
    border-radius: var(--radius-md);
    margin-bottom: var(--spacing-lg);
    color: var(--text-secondary);
    font-size: 0.9375rem;
}

/* Results Container */
.results-container {
    background: var(--bg-secondary);
    border-radius: var(--radius-lg);
    padding: var(--spacing-lg);
    margin-top: var(--spacing-lg);
    border: 1px solid var(--border);
}

.results-container:empty {
    display: none;
}

.results-container h4 {
    color: var(--primary);
    margin-bottom: var(--spacing-md);
    font-size: 1.125rem;
}

.result-item {
    display: flex;
    justify-content: space-between;
    align-items: center;
    padding: var(--spacing-sm) 0;
    border-bottom: 1px solid var(--border);
}

.result-item:last-child {
    border-bottom: none;
}

.result-label {
    color: var(--text-secondary);
    font-size: 0.9375rem;
}

.result-value {
    color: var(--text-primary);
    font-weight: 500;
}

.result-highlight {
    color: var(--primary);
    font-weight: 600;
    font-size: 1.125rem;
}

/* Alerts */
.alert {
    padding: var(--spacing-md);
    border-radius: var(--radius-md);
    margin-top: var(--spacing-lg);
    border-left: 4px solid;
}

.alert ul {
    margin: var(--spacing-sm) 0 0 var(--spacing-lg);
}

.alert li {
    margin-bottom: var(--spacing-xs);
}

.alert-warning {
    background: rgba(243, 156, 18, 0.1);
    border-color: var(--warning);
    color: var(--warning);
}

.alert-danger {
    background: rgba(231, 76, 60, 0.1);
    border-color: var(--danger);
    color: var(--danger);
}

.alert-success {
    background: rgba(46, 204, 113, 0.1);
    border-color: var(--secondary);
    color: var(--secondary);
}

.alert-info {
    background: rgba(52, 152, 219, 0.1);
    border-color: var(--info);
    color: var(--info);
}

/* Regimen Card */
.regimen-card {
    background: var(--bg-tertiary);
    border-left: 4px solid var(--warning);
    border-radius: var(--radius-md);
    padding: var(--spacing-md);
    margin-top: var(--spacing-md);
}

.regimen-card h5 {
    color: var(--warning);
    margin-bottom: var(--spacing-md);
}

/* Footer */
.footer {
    background: var(--bg-secondary);
    border-top: 1px solid var(--border);
    padding: var(--spacing-lg) 0;
    text-align: center;
    margin-top: auto;
}

.footer p {
    color: var(--text-secondary);
    font-size: 0.875rem;
    margin-bottom: var(--spacing-xs);
}

.disclaimer {
    color: var(--text-muted);
    font-size: 0.8125rem;
}

/* Utility Classes */
.hidden {
    display: none !important;
}

.text-center {
    text-align: center;
}

.mt-sm { margin-top: var(--spacing-sm); }
.mt-md { margin-top: var(--spacing-md); }
.mt-lg { margin-top: var(--spacing-lg); }

.mb-sm { margin-bottom: var(--spacing-sm); }
.mb-md { margin-bottom: var(--spacing-md); }
.mb-lg { margin-bottom: var(--spacing-lg); }

/* Responsive Design */
@media (max-width: 768px) {
    html {
        font-size: 14px;
    }
    
    .container {
        padding: 0 var(--spacing-sm);
    }
    
    .card-grid {
        grid-template-columns: repeat(2, 1fr);
    }
    
    .form-row {
        grid-template-columns: 1fr;
    }
    
    .conversion-inputs {
        grid-template-columns: 1fr;
    }
    
    .btn-swap {
        transform: rotate(90deg);
        margin: var(--spacing-sm) 0;
    }
    
    .module-nav {
        gap: var(--spacing-xs);
    }
    
    .module-tab {
        font-size: 0.8125rem;
        padding: var(--spacing-xs) var(--spacing-sm);
    }
}

@media (max-width: 480px) {
    .card-grid {
        grid-template-columns: 1fr;
    }
    
    .logo h1 {
        font-size: 1.25rem;
    }
}

/* Print Styles */
@media print {
    .header,
    .footer,
    .module-nav,
    .sub-module-nav,
    .quick-access,
    .btn {
        display: none;
    }
    
    body {
        background: white;
        color: black;
    }
    
    .results-container {
        border: 1px solid #000;
    }
}

/* ============================================
   DRUG REFERENCE MODULE
   ============================================ */

/* Search Section */
.drug-search-section {
    background: var(--bg-secondary);
    border-radius: var(--radius-lg);
    padding: var(--spacing-lg);
    margin-bottom: var(--spacing-lg);
    border: 1px solid var(--border);
}

.search-tabs {
    display: flex;
    gap: var(--spacing-xs);
    margin-bottom: var(--spacing-lg);
    overflow-x: auto;
    padding-bottom: var(--spacing-sm);
    scrollbar-width: thin;
    scrollbar-color: var(--border) transparent;
}

.search-tabs::-webkit-scrollbar {
    height: 6px;
}

.search-tabs::-webkit-scrollbar-track {
    background: transparent;
}

.search-tabs::-webkit-scrollbar-thumb {
    background: var(--border);
    border-radius: 3px;
}

.search-tab {
    background: var(--bg-tertiary);
    border: 1px solid var(--border);
    color: var(--text-secondary);
    padding: var(--spacing-sm) var(--spacing-md);
    border-radius: var(--radius-md);
    cursor: pointer;
    transition: var(--transition);
    white-space: nowrap;
    font-size: 0.875rem;
    font-weight: 500;
}

.search-tab:hover {
    background: var(--bg-secondary);
    color: var(--text-primary);
}

.search-tab.active {
    background: var(--primary);
    border-color: var(--primary);
    color: white;
}

.search-panel {
    display: none;
}

.search-panel.active {
    display: block;
    animation: fadeIn 0.3s ease;
}

.search-input-group {
    display: flex;
    gap: var(--spacing-sm);
    margin-bottom: var(--spacing-md);
}

.search-input-group input {
    flex: 1;
    padding: 12px 16px;
    background: var(--bg-primary);
    border: 2px solid var(--border);
    border-radius: var(--radius-md);
    color: var(--text-primary);
    font-size: 1rem;
    transition: var(--transition);
}

.search-input-group input:focus {
    outline: none;
    border-color: var(--primary);
    box-shadow: 0 0 0 3px rgba(52, 152, 219, 0.1);
}

.search-input-group .btn {
    display: flex;
    align-items: center;
    gap: var(--spacing-xs);
    padding: 12px 24px;
}

.filter-select {
    width: 100%;
    padding: 12px;
    background: var(--bg-primary);
    border: 2px solid var(--border);
    border-radius: var(--radius-md);
    color: var(--text-primary);
    font-size: 1rem;
    transition: var(--transition);
}

.filter-select:focus {
    outline: none;
    border-color: var(--primary);
    box-shadow: 0 0 0 3px rgba(52, 152, 219, 0.1);
}

/* Drug Suggestions (Autocomplete) */
.drug-suggestions {
    background: var(--bg-primary);
    border: 1px solid var(--border);
    border-radius: var(--radius-md);
    max-height: 300px;
    overflow-y: auto;
    display: none;
}

.drug-suggestions.active {
    display: block;
}

.suggestion-item {
    padding: var(--spacing-sm) var(--spacing-md);
    cursor: pointer;
    transition: var(--transition);
    border-bottom: 1px solid var(--border);
}

.suggestion-item:last-child {
    border-bottom: none;
}

.suggestion-item:hover {
    background: var(--bg-tertiary);
}

.suggestion-name {
    font-weight: 500;
    color: var(--text-primary);
}

.suggestion-category {
    font-size: 0.8125rem;
    color: var(--text-secondary);
    margin-top: 2px;
}

/* Drug Results Section */
.drug-results-section {
    display: none;
}

.drug-results-section.active {
    display: block;
    animation: fadeIn 0.3s ease;
}

.drug-card {
    background: var(--bg-secondary);
    border: 1px solid var(--border);
    border-radius: var(--radius-lg);
    padding: var(--spacing-lg);
    margin-bottom: var(--spacing-lg);
}

.drug-card-header {
    display: flex;
    justify-content: space-between;
    align-items: start;
    margin-bottom: var(--spacing-lg);
    padding-bottom: var(--spacing-md);
    border-bottom: 2px solid var(--border);
}

.drug-title-section h3 {
    font-size: 1.5rem;
    color: var(--primary);
    margin-bottom: var(--spacing-xs);
}

.drug-generic-name {
    font-size: 0.9375rem;
    color: var(--text-secondary);
    font-style: italic;
}

.drug-badges {
    display: flex;
    flex-wrap: wrap;
    gap: var(--spacing-xs);
    margin-top: var(--spacing-sm);
}

.drug-badge {
    display: inline-block;
    padding: 4px 12px;
    border-radius: 12px;
    font-size: 0.75rem;
    font-weight: 500;
    text-transform: uppercase;
    letter-spacing: 0.5px;
}

.badge-category {
    background: rgba(52, 152, 219, 0.2);
    color: var(--primary);
}

.badge-schedule {
    background: rgba(231, 76, 60, 0.2);
    color: var(--danger);
}

.badge-prescription {
    background: rgba(243, 156, 18, 0.2);
    color: var(--warning);
}

.badge-otc {
    background: rgba(46, 204, 113, 0.2);
    color: var(--secondary);
}

/* Drug Info Sections */
.drug-info-section {
    margin-bottom: var(--spacing-lg);
}

.drug-info-section:last-child {
    margin-bottom: 0;
}

.drug-info-section h4 {
    color: var(--text-primary);
    font-size: 1.125rem;
    margin-bottom: var(--spacing-md);
    display: flex;
    align-items: center;
    gap: var(--spacing-sm);
}

.drug-info-section h4::before {
    content: '';
    width: 4px;
    height: 20px;
    background: var(--primary);
    border-radius: 2px;
}

.formulation-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: var(--spacing-md);
}

.formulation-card {
    background: var(--bg-tertiary);
    border: 1px solid var(--border);
    border-radius: var(--radius-md);
    padding: var(--spacing-md);
}

.formulation-type {
    font-weight: 600;
    color: var(--primary);
    margin-bottom: var(--spacing-xs);
    text-transform: capitalize;
}

.formulation-details {
    font-size: 0.875rem;
    color: var(--text-secondary);
}

.formulation-details strong {
    color: var(--text-primary);
    display: block;
    margin-top: var(--spacing-xs);
}

.formulation-list {
    list-style: none;
    padding: 0;
    margin: var(--spacing-xs) 0 0 0;
}

.formulation-list li {
    padding: 4px 0;
    color: var(--text-secondary);
}

.formulation-list li::before {
    content: '•';
    color: var(--primary);
    margin-right: var(--spacing-xs);
}

/* Indications & Contraindications */
.indication-list,
.contraindication-list,
.adverse-effect-list {
    list-style: none;
    padding: 0;
    margin: 0;
}

.indication-item,
.contraindication-item {
    background: var(--bg-tertiary);
    border-left: 4px solid var(--secondary);
    padding: var(--spacing-md);
    margin-bottom: var(--spacing-sm);
    border-radius: var(--radius-sm);
}

.contraindication-item {
    border-left-color: var(--danger);
}

.indication-name,
.contraindication-name {
    font-weight: 600;
    color: var(--text-primary);
    margin-bottom: var(--spacing-xs);
}

.indication-details,
.contraindication-details {
    font-size: 0.875rem;
    color: var(--text-secondary);
    line-height: 1.5;
}

/* Adverse Effects */
.adverse-effects-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: var(--spacing-md);
}

.adverse-effect-category {
    background: var(--bg-tertiary);
    border: 1px solid var(--border);
    border-radius: var(--radius-md);
    padding: var(--spacing-md);
}

.adverse-effect-category h5 {
    color: var(--warning);
    font-size: 1rem;
    margin-bottom: var(--spacing-sm);
}

.adverse-effect-list {
    font-size: 0.875rem;
}

.adverse-effect-list li {
    padding: 4px 0;
    color: var(--text-secondary);
    display: flex;
    align-items: start;
    gap: var(--spacing-xs);
}

.adverse-effect-list li::before {
    content: '⚠';
    color: var(--warning);
    flex-shrink: 0;
    margin-top: 2px;
}

.severity-badge {
    display: inline-block;
    padding: 2px 8px;
    border-radius: 8px;
    font-size: 0.6875rem;
    font-weight: 600;
    text-transform: uppercase;
    margin-left: var(--spacing-xs);
}

.severity-common {
    background: rgba(46, 204, 113, 0.2);
    color: var(--secondary);
}

.severity-serious {
    background: rgba(243, 156, 18, 0.2);
    color: var(--warning);
}

.severity-severe {
    background: rgba(231, 76, 60, 0.2);
    color: var(--danger);
}

/* No Results */
.no-results {
    text-align: center;
    padding: var(--spacing-xl);
    color: var(--text-secondary);
}

.no-results-icon {
    font-size: 3rem;
    margin-bottom: var(--spacing-md);
    opacity: 0.5;
}

/* Multiple Results List */
.drug-list {
    display: grid;
    gap: var(--spacing-md);
}

.drug-list-item {
    background: var(--bg-tertiary);
    border: 1px solid var(--border);
    border-radius: var(--radius-md);
    padding: var(--spacing-md);
    cursor: pointer;
    transition: var(--transition);
}

.drug-list-item:hover {
    background: var(--bg-secondary);
    border-color: var(--primary);
    transform: translateX(4px);
}

.drug-list-item h4 {
    color: var(--primary);
    margin-bottom: var(--spacing-xs);
}

.drug-list-item p {
    color: var(--text-secondary);
    font-size: 0.875rem;
    margin: 0;
}

/* Responsive */
@media (max-width: 768px) {
    .search-input-group {
        flex-direction: column;
    }
    
    .formulation-grid,
    .adverse-effects-grid {
        grid-template-columns: 1fr;
    }
    
    .drug-card-header {
        flex-direction: column;
        gap: var(--spacing-md);
    }
}

/* Logo with Connection Indicator */
.logo {
    display: flex;
    align-items: center;
    gap: var(--spacing-sm);
    position: relative;
}

.logo h1 {
    font-size: 1.5rem;
    margin: 0;
    font-weight: 700;
    background: linear-gradient(135deg, var(--primary), var(--secondary));
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent;
    background-clip: text;
}

/* Connection Indicator */
.connection-indicator {
    display: flex;
    align-items: center;
    justify-content: center;
    cursor: pointer;
    margin-left: 4px;
    position: relative;
}

.connection-indicator svg {
    display: block;
}

.indicator-bg {
    fill: var(--bg-tertiary);
    transition: fill 0.3s ease;
}

.indicator-dot {
    transition: fill 0.3s ease, filter 0.3s ease;
}

/* Checking state - gray pulsing */
.connection-indicator.checking .indicator-bg {
    fill: rgba(128, 128, 128, 0.2);
}

.connection-indicator.checking .indicator-dot {
    fill: #808080;
    animation: pulse 1.5s ease-in-out infinite;
}

/* Connected state - green glowing */
.connection-indicator.connected .indicator-bg {
    fill: rgba(46, 204, 113, 0.2);
}

.connection-indicator.connected .indicator-dot {
    fill: #2ecc71;
    filter: drop-shadow(0 0 4px rgba(46, 204, 113, 0.8));
}

/* Disconnected state - yellow/orange */
.connection-indicator.disconnected .indicator-bg {
    fill: rgba(243, 156, 18, 0.2);
}

.connection-indicator.disconnected .indicator-dot {
    fill: #f39c12;
    filter: drop-shadow(0 0 4px rgba(243, 156, 18, 0.8));
}

/* Degraded state - orange */
.connection-indicator.degraded .indicator-bg {
    fill: rgba(230, 126, 34, 0.2);
}

.connection-indicator.degraded .indicator-dot {
    fill: #e67e22;
    filter: drop-shadow(0 0 4px rgba(230, 126, 34, 0.8));
}

/* Hover effect */
.connection-indicator:hover .indicator-bg {
    fill: var(--bg-secondary);
}

/* Tooltip */
.connection-indicator::before {
    content: attr(data-tooltip);
    position: absolute;
    bottom: -40px;
    left: 50%;
    transform: translateX(-50%);
    padding: 8px 12px;
    background: var(--bg-primary);
    border: 1px solid var(--border);
    border-radius: var(--radius-md);
    font-size: 0.75rem;
    color: var(--text-secondary);
    white-space: nowrap;
    opacity: 0;
    pointer-events: none;
    transition: opacity 0.2s;
    z-index: 1000;
    box-shadow: var(--shadow-md);
}

.connection-indicator:hover::before {
    opacity: 1;
}

/* Pulse animation for checking state */
@keyframes pulse {
    0%, 100% {
        opacity: 1;
    }
    50% {
        opacity: 0.4;
    }
}

/* Responsive adjustments */
@media (max-width: 768px) {
    .logo h1 {
        font-size: 1.25rem;
    }
    
    .connection-indicator {
        margin-left: 2px;
    }
    
    .connection-indicator svg {
        width: 14px;
        height: 14px;
    }
    
    .connection-indicator::before {
        bottom: -45px;
        font-size: 0.6875rem;
    }
}

@media (max-width: 480px) {
    .logo h1 {
        font-size: 1.125rem;
    }
    
    .connection-indicator svg {
        width: 12px;
        height: 12px;
    }
}

/* ============================================
   PEDIATRIC DOSING TABLES
   ============================================ */

.pediatric-dosing-guideline {
    background: var(--bg-tertiary);
    border: 1px solid var(--border);
    border-radius: var(--radius-md);
    padding: var(--spacing-lg);
    margin-bottom: var(--spacing-md);
}

.pediatric-dosing-guideline:last-child {
    margin-bottom: 0;
}

.pediatric-dosing-guideline h5 {
    color: var(--secondary);
    font-size: 1.125rem;
    margin-bottom: var(--spacing-sm);
}

.indication-context {
    color: var(--text-secondary);
    font-size: 0.9375rem;
    margin-bottom: var(--spacing-md);
    padding: var(--spacing-sm);
    background: var(--bg-secondary);
    border-left: 3px solid var(--secondary);
    border-radius: var(--radius-sm);
}

.pediatric-dosing-table-container {
    overflow-x: auto;
    margin: var(--spacing-md) 0;
    border-radius: var(--radius-md);
    box-shadow: var(--shadow-sm);
}

.pediatric-dosing-table {
    width: 100%;
    border-collapse: collapse;
    background: var(--bg-secondary);
    font-size: 0.875rem;
}

.pediatric-dosing-table thead {
    background: var(--bg-primary);
}

.pediatric-dosing-table th {
    padding: var(--spacing-md);
    text-align: left;
    font-weight: 600;
    color: var(--primary);
    border-bottom: 2px solid var(--border);
    white-space: nowrap;
}

.pediatric-dosing-table tbody tr {
    border-bottom: 1px solid var(--border);
    transition: background-color 0.2s ease;
}

.pediatric-dosing-table tbody tr:last-child {
    border-bottom: none;
}

.pediatric-dosing-table tbody tr:hover {
    background: var(--bg-tertiary);
}

.pediatric-dosing-table td {
    padding: var(--spacing-md);
    color: var(--text-secondary);
}

.weight-band-cell {
    font-weight: 600;
    color: var(--text-primary) !important;
    white-space: nowrap;
}

.dose-cell {
    font-weight: 500;
    color: var(--secondary) !important;
}

.dosing-reference {
    font-size: 0.8125rem;
    color: var(--text-muted);
    font-style: italic;
    margin: var(--spacing-sm) 0 0 0;
}

.dosing-notes {
    font-size: 0.875rem;
    color: var(--text-secondary);
    margin: var(--spacing-sm) 0 0 0;
    padding: var(--spacing-sm);
    background: rgba(243, 156, 18, 0.1);
    border-left: 3px solid var(--warning);
    border-radius: var(--radius-sm);
}

/* Responsive table */
@media (max-width: 768px) {
    .pediatric-dosing-table {
        font-size: 0.8125rem;
    }
    
    .pediatric-dosing-table th,
    .pediatric-dosing-table td {
        padding: var(--spacing-sm);
    }
}

@media (max-width: 480px) {
    .pediatric-dosing-table-container {
        margin: var(--spacing-sm) -var(--spacing-md);
        border-radius: 0;
    }
    
    .pediatric-dosing-table {
        font-size: 0.75rem;
    }
    
    .pediatric-dosing-table th,
    .pediatric-dosing-table td {
        padding: var(--spacing-xs) var(--spacing-sm);
    }
}